Human N myc interactor (NMI) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NMI
Locus ID	9111
Kit Components	GA106066G1, N myc interactor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106066G2, N myc interactor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106066G3, N myc interactor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004688
Synonyms	N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor
Summary	NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

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