Human LDB2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LDB2
Locus ID	9079
Kit Components	GA106040G1, LDB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106040G2, LDB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106040G3, LDB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130834, NM_001290, NM_001304434, NM_001304435, NR_130734
Synonyms	CLIM1; LDB-2; LDB1
Summary	The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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