Human HIP1R activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HIP1R
Locus ID	9026
Kit Components	GA105999G1, HIP1R gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105999G2, HIP1R gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105999G3, HIP1R gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001303097, NM_001303099, NM_003959
Synonyms	HIP3; HIP12; ILWEQ
Summary	Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.[UniProtKB/Swiss-Prot Function]

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