Human P4HA2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P4HA2
Locus ID	8974
Kit Components	GA105970G1, P4HA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105970G2, P4HA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105970G3, P4HA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001017973, NM_001017974, NM_001142598, NM_001142599, NM_004199, NM_001365679, NM_001365680, NM_001365681, NM_001365677, NM_001365678
Synonyms	4-PH alpha 2
Summary	This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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