Human EIF2S2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF2S2
Locus ID	8894
Kit Components	GA105925G1, EIF2S2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105925G2, EIF2S2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105925G3, EIF2S2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001316363, NM_001316364, NM_003908
Synonyms	eIF-2-beta; EIF2; EIF2B; EIF2beta; PPP1R67
Summary	Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

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