Human ZNF259 (ZPR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZPR1
Locus ID	8882
Kit Components	GA105915G1, ZNF259 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105915G2, ZNF259 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105915G3, ZNF259 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317086, NM_003904
Synonyms	ZNF259
Summary	The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

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