Human NRP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NRP2
Locus ID	8828
Kit Components	GA105871G1, NRP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105871G2, NRP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105871G3, NRP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003872, NM_018534, NM_201264, NM_201266, NM_201267, NM_201279
Synonyms	NP2; NPN2; PRO2714; VEGF165R2
Summary	This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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