Human NCOA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCOA1
Locus ID	8648
Kit Components	GA105731G1, NCOA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105731G2, NCOA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105731G3, NCOA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003743, NM_147223, NM_147233, NM_001362950, NM_001362952, NM_001362954, NM_001362955
Synonyms	bHLHe42; bHLHe74; F-SRC-1; KAT13A; RIP160; SRC1
Summary	The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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