Human SKAP55 (SKAP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SKAP1
Locus ID	8631
Kit Components	GA105715G1, SKAP55 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105715G2, SKAP55 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105715G3, SKAP55 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001075099, NM_003726
Synonyms	HEL-S-81p; SCAP1; SKAP55
Summary	This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]

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