Human HSD17B6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSD17B6
Locus ID	8630
Kit Components	GA105714G1, HSD17B6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105714G2, HSD17B6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105714G3, HSD17B6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003725
Synonyms	HSE; RODH; SDR9C6
Summary	The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]

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