Human Retinol dehydrogenase 16 (RDH16) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RDH16
Locus ID	8608
Kit Components	GA105698G1, Retinol dehydrogenase 16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105698G2, Retinol dehydrogenase 16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105698G3, Retinol dehydrogenase 16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320108, NM_003708
Synonyms	RODH-4; SDR9C8
Summary	Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes (PubMed:10329026, PubMed:12534290, PubMed:9677409). Has higher activity towards CRBP-bound retinol than with free retinol (PubMed:12534290). Oxidizes also 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction (PubMed:10329026, PubMed:9677409, PubMed:29541409).[UniProtKB/Swiss-Prot Function]

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