Human DEGS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DEGS1
Locus ID	8560
Kit Components	GA105672G1, DEGS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105672G2, DEGS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105672G3, DEGS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001321541, NM_001321542, NM_003676, NM_144780
Synonyms	DEGS; DEGS-1; Des-1; DES1; FADS7; MIG15; MLD
Summary	This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]

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