Human Alkyl DHAP synthase (AGPS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AGPS
Locus ID	8540
Kit Components	GA105654G1, Alkyl DHAP synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105654G2, Alkyl DHAP synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105654G3, Alkyl DHAP synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003659
Synonyms	ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3
Summary	This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]

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