Human CDC42 binding protein kinase alpha (CDC42BPA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDC42BPA
Locus ID	8476
Kit Components	GA105600G1, CDC42 binding protein kinase alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105600G2, CDC42 binding protein kinase alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105600G3, CDC42 binding protein kinase alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003607, NM_014826, NM_001366010, NM_001366011, NM_001366019
Synonyms	MRCK; MRCKA; PK428
Summary	The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]

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