Human FKLF / KLF11 (KLF11) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLF11
Locus ID	8462
Kit Components	GA105592G1, FKLF / KLF11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105592G2, FKLF / KLF11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105592G3, FKLF / KLF11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001177716, NM_001177718, NM_003597
Synonyms	FKLF; FKLF1; MODY7; TIEG2; Tieg3
Summary	The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

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