Human DOC2A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOC2A
Locus ID	8448
Kit Components	GA105580G1, DOC2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105580G2, DOC2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105580G3, DOC2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282062, NM_001282063, NM_001282068, NM_003586, NR_104089, NR_104090
Synonyms	Doc2
Summary	There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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