Human Nck beta (NCK2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCK2
Locus ID	8440
Kit Components	GA105574G1, Nck beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105574G2, Nck beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105574G3, Nck beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001004720, NM_001004722, NM_003581
Synonyms	GRB4; NCKbeta
Summary	This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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