Human RECK activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RECK
Locus ID	8434
Kit Components	GA105568G1, RECK gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105568G2, RECK gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105568G3, RECK gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001316345, NM_001316346, NM_001316347, NM_001316348, NM_021111
Synonyms	ST15
Summary	The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

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