Human MAD1 (MAD1L1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAD1L1
Locus ID	8379
Kit Components	GA105535G1, MAD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105535G2, MAD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105535G3, MAD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013836, NM_001013837, NM_001304523, NM_001304524, NM_001304525, NM_003550
Synonyms	MAD1; PIG9; TP53I9; TXBP181
Summary	MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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