Human TRRAP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRRAP
Locus ID	8295
Kit Components	GA105473G1, TRRAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105473G2, TRRAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105473G3, TRRAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001244580, NM_003496
Synonyms	PAF350/400; PAF400; STAF40; TR-AP; Tra1
Summary	This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

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