Human LAGE3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LAGE3
Locus ID	8270
Kit Components	GA105461G1, LAGE3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105461G2, LAGE3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105461G3, LAGE3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006014
Synonyms	CVG5; DXS9879E; DXS9951E; ESO3; ITBA2; Pcc1
Summary	This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]

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