Human ESS2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ESS2
Locus ID	8220
Kit Components	GA105445G1, ESS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105445G2, ESS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105445G3, ESS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022719, NR_134304
Synonyms	DGCR13; DGS-H; DGS-I; DGSH; DGSI; ES2; Es2el
Summary	This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

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