Human FGF 23 (FGF23) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FGF23
Locus ID	8074
Kit Components	GA105400G1, FGF 23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105400G2, FGF 23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105400G3, FGF 23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020638
Synonyms	ADHR; FGFN; HPDR2; HYPF; PHPTC
Summary	This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]

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