Human ADAM12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADAM12
Locus ID	8038
Kit Components	GA105393G1, ADAM12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105393G2, ADAM12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105393G3, ADAM12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001288973, NM_001288974, NM_001288975, NM_003474, NM_021641
Synonyms	ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA
Summary	This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]

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