Human STAM1 (STAM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STAM
Locus ID	8027
Kit Components	GA105386G1, STAM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105386G2, STAM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105386G3, STAM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003473, NR_037774, NM_001324282, NM_001324283, NM_001324284, NM_001324285, NM_001324286, NM_001324287, NM_001324288, NM_001324289
Synonyms	STAM-1; STAM1
Summary	This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

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