Human ARHGEF5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF5
Locus ID	7984
Kit Components	GA105375G1, ARHGEF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105375G2, ARHGEF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105375G3, ARHGEF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002861, NM_005435
Synonyms	DKFZp686N1969; GEF5; guanine nucleotide regulatory protein TIM; P60; P60, TIM, GEF5, TIM1, DKFZp686N1969; Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5; TIM; TIM1; transforming immortalized mammary oncogene
Summary	Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]

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