Human CNBP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CNBP
Locus ID	7555
Kit Components	GA105202G1, CNBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105202G2, CNBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105202G3, CNBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127192, NM_001127193, NM_001127194, NM_001127195, NM_001127196, NM_003418
Synonyms	CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9
Summary	This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]

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