Human 14 3 3 gamma (YWHAG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	YWHAG
Locus ID	7532
Kit Components	GA105183G1, 14 3 3 gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105183G2, 14 3 3 gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105183G3, 14 3 3 gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012479
Synonyms	14-3-3GAMMA; PPP1R170
Summary	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

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