Human WNT7A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WNT7A
Locus ID	7476
Kit Components	GA105152G1, WNT7A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105152G2, WNT7A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105152G3, WNT7A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004625
Synonyms	AI849442; OTTMUSP00000024971; postaxial hemimelia; px; tw; wingless-related MMTV integration site 7A; Wnt-7a
Summary	This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]

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