Human Tryptophanyl tRNA synthetase (WARS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WARS1
Locus ID	7453
Kit Components	GA105135G1, Tryptophanyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105135G2, Tryptophanyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105135G3, Tryptophanyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004184, NM_173701, NM_213645, NM_213646
Synonyms	GAMMA-2; IFI53; IFP53
Summary	Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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