Human CLRN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLRN1
Locus ID	7401
Kit Components	GA105098G1, CLRN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105098G2, CLRN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105098G3, CLRN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001195794, NM_001256819, NM_052995, NM_174878, NM_174879, NM_174880, NR_046380
Synonyms	RP61; USH3; USH3A
Summary	This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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