Human UGT2B7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UGT2B7
Locus ID	7364
Kit Components	GA105072G1, UGT2B7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105072G2, UGT2B7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105072G3, UGT2B7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001074, NM_001330719, NM_001349568
Synonyms	UDPGT2B7; UDPGT 2B9; UDPGTH2; UGT2B9
Summary	The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]

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