Human Transcription termination factor 1 (TTF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TTF1
Locus ID	7270
Kit Components	GA105005G1, Transcription termination factor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105005G2, Transcription termination factor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105005G3, Transcription termination factor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205296, NM_007344, NR_134525
Synonyms	TTF-1; TTF-I
Summary	This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011]

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