Human TSH Receptor (TSHR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSHR
Locus ID	7253
Kit Components	GA104990G1, TSH Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104990G2, TSH Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104990G3, TSH Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000369, NM_001018036, NM_001142626
Synonyms	CHNG1; hTSHR-I; LGR3
Summary	The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

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