Human TNFAIP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFAIP3
Locus ID	7128
Kit Components	GA104922G1, TNFAIP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104922G2, TNFAIP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104922G3, TNFAIP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001270507, NM_001270508, NM_006290
Synonyms	A20; AISBL; OTUD7C; TNFA1P2
Summary	This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]

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