Human Troponin C (TNNC2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNNC2
Locus ID	7125
Kit Components	GA104919G1, Troponin C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104919G2, Troponin C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104919G3, Troponin C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003279
Synonyms	fast skeletal muscle troponin C; OTTHUMP00000039531; troponin C2, fast; troponin C type 2 (fast)
Summary	Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]

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