Human TLE2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TLE2
Locus ID	7089
Kit Components	GA104890G1, TLE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104890G2, TLE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104890G3, TLE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144761, NM_001144762, NM_001300846, NM_003260
Synonyms	ESG; ESG2; GRG2
Summary	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).[UniProtKB/Swiss-Prot Function]

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