Human TIMP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TIMP3
Locus ID	7078
Kit Components	GA104881G1, TIMP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104881G2, TIMP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104881G3, TIMP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000362
Synonyms	HSMRK222; K222; K222TA2; SFD
Summary	This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]

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