Human Transglutaminase 3 (TGM3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TGM3
Locus ID	7053
Kit Components	GA104860G1, Transglutaminase 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104860G2, Transglutaminase 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104860G3, Transglutaminase 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003245, N23065
Synonyms	TGE
Summary	Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]

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