Human TAT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TAT
Locus ID	6898
Kit Components	GA104754G1, TAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104754G2, TAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104754G3, TAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000353
Synonyms	tyrosine aminotransferase; tyrosine aminotransferase, cytosolic
Summary	This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008]

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