Human Somatostatin Receptor 5 (SSTR5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SSTR5
Locus ID	6755
Kit Components	GA104648G1, Somatostatin Receptor 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104648G2, Somatostatin Receptor 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104648G3, Somatostatin Receptor 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001053, NM_001172560, NM_001172572, NM_001172573
Synonyms	SS-5-R
Summary	Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]

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