Human SPARC activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPARC
Locus ID	6678
Kit Components	GA104585G1, SPARC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104585G2, SPARC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104585G3, SPARC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001309444, NM_003118, NM_001309443
Synonyms	BM-40; OI17; ON
Summary	This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]

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