Human beta Synuclein (SNCB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNCB
Locus ID	6620
Kit Components	GA104533G1, beta Synuclein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104533G2, beta Synuclein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104533G3, beta Synuclein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001502, NM_001318034, NM_001318035, NM_001318036, NM_001318037, NM_003085, NM_001363140
Synonyms	beta-synuclein; synuclein, beta
Summary	This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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