Human Sialoadhesin (SIGLEC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SIGLEC1
Locus ID	6614
Kit Components	GA104527G1, Sialoadhesin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104527G2, Sialoadhesin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104527G3, Sialoadhesin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023068, NM_001367089
Synonyms	CD169; dJ1009E24.1; SIGLEC-1; SN
Summary	This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

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