Human Helicase SKI2W (SKIV2L) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SKIV2L
Locus ID	6499
Kit Components	GA104425G1, Helicase SKI2W gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104425G2, Helicase SKI2W gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104425G3, Helicase SKI2W gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006929
Synonyms	170A; DDX13; HLP; SKI2; SKI2W; SKIV2; SKIV2L1; THES2
Summary	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

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