Human delta Sarcoglycan (SGCD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SGCD
Locus ID	6444
Kit Components	GA104385G1, delta Sarcoglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104385G2, delta Sarcoglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104385G3, delta Sarcoglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000337, NM_001128209, NM_172244
Synonyms	35DAG; CMD1L; DAGD; SG-delta; SGCDP; SGD
Summary	The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

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