Human SETMAR activation kit by CRISPRa
CAT#: GA104365
SETMAR CRISPRa kit - CRISPR gene activation of human SET domain and mariner transposase fusion gene
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SETMAR |
Locus ID | 6419 |
Kit Components | GA104365G1, SETMAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104365G2, SETMAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104365G3, SETMAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001243723, NM_001276325, NM_001320676, NM_001320677, NM_001320678, NM_006515, NR_024022, NR_075073 |
Synonyms | Mar1; METNASE |
Summary | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN422705 | SETMAR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |