Human SETMAR activation kit by CRISPRa

CAT#: GA104365

SETMAR CRISPRa kit - CRISPR gene activation of human SET domain and mariner transposase fusion gene



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SETMAR
Locus ID 6419
Kit Components

GA104365G1, SETMAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104365G2, SETMAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104365G3, SETMAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001243723, NM_001276325, NM_001320676, NM_001320677, NM_001320678, NM_006515, NR_024022, NR_075073
Synonyms Mar1; METNASE
Summary This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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