Human CD62P (SELP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SELP
Locus ID	6403
Kit Components	GA104356G1, CD62P gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104356G2, CD62P gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104356G3, CD62P gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003005
Synonyms	CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL
Summary	This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

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