Human SCN4B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCN4B
Locus ID	6330
Kit Components	GA104296G1, SCN4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104296G2, SCN4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104296G3, SCN4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142348, NM_001142349, NM_174934, NR_024527
Synonyms	ATFB17; LQT10; Navbeta4
Summary	The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]

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