Human SERPINB4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SERPINB4
Locus ID	6318
Kit Components	GA104286G1, SERPINB4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104286G2, SERPINB4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104286G3, SERPINB4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002974, NM_175041
Synonyms	LEUPIN; PI11; SCCA-2; SCCA1; SCCA2
Summary	The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017]

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